Effects of dietary oyster peptide supplement on litter performance, immunological response of sows and growth performance of piglets

The results demonstrated that the supplementation of OPI to the diets of sows in late gestation and lactation resulted in a significant increase in the number of healthy piglets and weaning survival rate (<i>p</i> ≤ 0.05); colostrum and placenta samples were collected during parturition, IgA, IgG and IgM in colostrum of sows also increased (<i>p</i> ≤ 0.05); expression levels of glucose transporter genes (<i>GLUT4</i>, <i>SLC2A1</i>), amino acid transporter genes (<i>SNAT1</i>, <i>LAT1</i>), and fatty acid transporter genes (<i>FABP3</i>) in the placenta were increased (<i>p</i> ≤ 0.05). The levels of pro-inflammatory factors (<i>IL-1</i>, <i>IL-6</i>, <i>IL-8</i>, <i>AVPI1</i> were significantly decreased in the placenta, whereas the levels of anti-inflammatory factors (<i>IL-10</i>), antioxidant genes (<i>SOD1</i>, <i>SOD2</i>, <i>GPX2</i>, <i>CAT</i>), and anti-apoptotic genes (<i>BCL2</i>, <i>BCL2L1</i>) were sign.