Overexpression of HNF4G can Increase the Resistance of Ovarian Cancer Cells to Olaparib
Overexpression of HNF4G plays a crucial role in conferring Olaparib resistance in OV by activating the PI3K-AKT signaling pathway. HNF4G may serve as a potential therapeutic target for patients with Olaparib-resistant OV.
Authors
- Yue Deng (ORCID: https://orcid.org/0000-0003-2871-8922)
- Lihua Yang (ORCID: https://orcid.org/0000-0002-6293-4816)
- Huilin Yang (ORCID: https://orcid.org/0000-0003-4637-5177)
- Qin Zhang (ORCID: https://orcid.org/0000-0002-0455-8138)
- Ying Dong (ORCID: https://orcid.org/0009-0009-9705-6097)
- Youfang Hou
Institutions
- Kunming Medical University (CN)
Publication Details
- Journal
- Current Cancer Drug Targets
- Published
- 2025-10-17
- DOI
- https://doi.org/10.2174/0115680096410121250926110350
- Primary Topic
- PARP inhibition in cancer therapy
- Type
- article
- Field-Weighted Citation Impact
- 0.00