Successful Treatment of Paediatric Necrobiosis Lipoidica With Baricitinib
ABSTRACT Necrobiosis lipoidica (NL) is a rare, chronic granulomatous condition that typically presents as sharply demarcated plaques with telangiectasia and atrophic centres. Paediatric cases are uncommon, and treatment options often fail to address refractory cases. We report a 13‐year‐old girl with progressive NL lesions that responded successfully to oral baricitinib, a Janus kinase inhibitor. Initial management with topical and systemic corticosteroids failed, but baricitinib led to significant lesion improvement within 6 months. This case highlights the potential of baricitinib in refractory paediatric NL and underscores the need for further research on its long‐term efficacy and safety.
Authors
- Maria João Paiva Lopes (ORCID: https://orcid.org/0000-0001-9189-2734)
- Pedro Simões Farinha (ORCID: https://orcid.org/0009-0006-2840-4228)
Institutions
- Unidade Local de Saúde de São José (PT)
- Hospital de São José (PT)
- Centro Hospitalar Lisboa Norte (PT)
- Universidade Nova de Lisboa (PT)
Publication Details
- Journal
- JEADV Clinical Practice
- Published
- 2025-10-21
- DOI
- https://doi.org/10.1002/jvc2.70194
- Primary Topic
- Skin Diseases and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00