A Cross‐Scale Memristor‐Based Neuromorphic Platform Bridging Physical Encoding and Medical Inference

Abstract Despite the progress in machine vision, existing image recognition systems still operate in isolation from the physical world, lacking dynamic temporal encoding, in‐memory processing, and intrinsic interpretability. Here, a memristive vision architecture that integrates multimodal sensing, physical memory, and medical inference within a unified device‐level framework is developed. Specifically, spatial gradients from retinal fundus images are encoded into Ag/Indigo/FTO memristor array via pulse modulation, generating conductance maps (“G maps”) that serve both as nonvolatile memory and as neuromorphic inputs for lesion segmentation via lightweight U‐Net models. Beyond static vision, the same memristor exhibits strong temporal sensitivity, enabling biologically realistic nociceptive encoding and Morse code recognition. These results demonstrate a cross‐task, cross‐scale system that merges physical encoding with machine intelligence, bridging the gap between material dynamics and high‐level perception. Therefore, this paradigm offers a scalable, interpretable hardware foundation for next‐generation bio‐perceptive computing and intelligent diagnostics.

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Publication Details

Journal
Advanced Functional Materials
Published
2025-10-21
DOI
https://doi.org/10.1002/adfm.202522229
Citations
1
Primary Topic
Advanced Memory and Neural Computing
Type
article
Field-Weighted Citation Impact
0.73

Funders

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article

A Cross‐Scale Memristor‐Based Neuromorphic Platform Bridging Physical Encoding and Medical Inference

Zelin Cao, Guangdong Zhou, Bai Tao Sun, Zhirong Liu et al.
1 citations
Advanced Functional Materials
Advanced Memory and Neural Computing
0.73
article

A Cross‐Scale Memristor‐Based Neuromorphic Platform Bridging Physical Encoding and Medical Inference

Zelin Cao, Guangdong Zhou, Bai Tao Sun, Zhirong Liu, Xiaobing Ren, Ye Lu, Song Wang, Kaikai Gao
article en
1 citations

Abstract

Abstract Despite the progress in machine vision, existing image recognition systems still operate in isolation from the physical world, lacking dynamic temporal encoding, in‐memory processing, and intrinsic interpretability. Here, a memristive vision architecture that integrates multimodal sensing, physical memory, and medical inference within a unified device‐level framework is developed. Specifically, spatial gradients from retinal fundus images are encoded into Ag/Indigo/FTO memristor array via pulse modulation, generating conductance maps (“G maps”) that serve both as nonvolatile memory and as neuromorphic inputs for lesion segmentation via lightweight U‐Net models. Beyond static vision, the same memristor exhibits strong temporal sensitivity, enabling biologically realistic nociceptive encoding and Morse code recognition. These results demonstrate a cross‐task, cross‐scale system that merges physical encoding with machine intelligence, bridging the gap between material dynamics and high‐level perception. Therefore, this paradigm offers a scalable, interpretable hardware foundation for next‐generation bio‐perceptive computing and intelligent diagnostics.

Advanced Functional MaterialsVol. 36(20)
Southwest University (CN), The Fourth People's Hospital (CN), Xi’an Children’s Hospital (CN), Xi'an Jiaotong University (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 22%
Advanced Memory and Neural Computing
0.73
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A Cross‐Scale Memristor‐Based Neuromorphic Platform Bridging Physical Encoding and Medical Inference — Zelin Cao, Guangdong Zhou, et al. · Advanced Functional Materials (2025) | TGRS Research Map | TGRS