The Effects of CD100 Stimulation on Primary Human Hepatocytes (PHHs) and Its Implications in HBV‐Related Liver Cirrhosis
CD100 stimulation on PHHs induced anti-cirrhosis gene expression and suppressed HSCs activation through ERK and STAT3 signaling, which may potentially serve as a target for the treatment of HBV-related liver cirrhosis.
Authors
- Bibo Kang
- Chuantao Ye (ORCID: https://orcid.org/0000-0002-6963-2757)
- Jianqi Lian (ORCID: https://orcid.org/0000-0002-5549-7590)
- Xiaojun He (ORCID: https://orcid.org/0009-0008-4313-6924)
- Xiaoyan Wang (ORCID: https://orcid.org/0000-0001-7406-5008)
- Fangfang Li (ORCID: https://orcid.org/0009-0007-2789-1981)
- Yi Li (ORCID: https://orcid.org/0000-0002-7871-5351)
- Hongyan Shi
- Jun Xiong (ORCID: https://orcid.org/0000-0003-2598-0706)
- Fang Zhao (ORCID: https://orcid.org/0009-0001-4551-8116)
- Chao Fan (ORCID: https://orcid.org/0000-0002-3834-6483)
- Yun Zhou (ORCID: https://orcid.org/0000-0002-2306-8986)
- Ping Xue (ORCID: https://orcid.org/0000-0003-3935-4845)
- Xuyang Zheng (ORCID: https://orcid.org/0000-0003-1614-8029)
- Xiǎoyīng Dèng (ORCID: https://orcid.org/0000-0003-0636-4414)
- Xilin Du
- Ying Zhang (ORCID: https://orcid.org/0000-0001-5476-1524)
Institutions
- Tang Du Hospital (CN)
- Air Force Medical University (CN)
Publication Details
- Journal
- Journal of Gastroenterology and Hepatology
- Published
- 2025-10-21
- DOI
- https://doi.org/10.1111/jgh.70123
- Primary Topic
- Vagus Nerve Stimulation Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China