Redefining neurocognitive outcomes after radiation for brain metastases: a patient-level meta-analysis of recovery following initial decline
A sizeable proportion of patients who experience NCF following brain radiation eventually attain full and sustained CR, thereby highlighting that neurocognitive decline may not be permanent. The use of conformal radiation techniques results in greater rates of neurocognitive recovery.
Authors
- Vinai Gondi
- Terri S. Armstrong (ORCID: https://orcid.org/0000-0002-2414-0492)
- Joshua D. Palmer (ORCID: https://orcid.org/0000-0003-3311-0129)
- Minesh P. Mehta (ORCID: https://orcid.org/0000-0002-4812-5713)
- Mark Vikas Mishra (ORCID: https://orcid.org/0000-0002-2588-1575)
- Kai Sun (ORCID: https://orcid.org/0000-0002-0305-2725)
- Paul D. Brown (ORCID: https://orcid.org/0000-0003-0022-4533)
- Søren M. Bentzen (ORCID: https://orcid.org/0000-0002-7444-7564)
- H.R.R. Cherng (ORCID: https://orcid.org/0000-0002-4817-1007)
Institutions
- University of Maryland, Baltimore (US)
- Baptist Hospital of Miami (US)
- University of Maryland Medical Center (US)
- Mayo Clinic (US)
- The Ohio State University Wexner Medical Center (US)
- Baptist Health South Florida (US)
- Mayo Clinic in Arizona (US)
- National Cancer Institute (US)
- Mayo Clinic in Florida (US)
- Northwestern Medicine (US)
- U-M Rogel Cancer Center (US)
Publication Details
- Journal
- JNCI Journal of the National Cancer Institute
- Published
- 2025-10-19
- DOI
- https://doi.org/10.1093/jnci/djaf264
- Citations
- 1
- Primary Topic
- Brain Metastases and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- National Institutes of Health
- National Cancer Institute