Baseline CSF ferritin levels were associated with trajectories of depressive symptoms among older people without dementia
Our study identified three distinct trajectories of depressive symptoms in older adults without dementia. We observed that lower CSF ferritin levels were associated with a higher likelihood of membership in the rapidly increasing symptom trajectory.
Authors
- Yongjian Lin (ORCID: https://orcid.org/0000-0003-2774-5814)
- Qing Wang (ORCID: https://orcid.org/0000-0002-1296-7097)
- Xinwu Ye
Institutions
- Wenzhou City People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Aging Neuroscience
- Published
- 2025-10-22
- DOI
- https://doi.org/10.3389/fnagi.2025.1516388
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. Department of Defense
- Alzheimer's Association
- Bristol-Myers Squibb
- Eli Lilly and Company
- Pfizer
- Biogen
- University of Southern California
- Meso Scale Diagnostics
- Alzheimer's Disease Neuroimaging Initiative
- BioClinica
- Novartis Pharmaceuticals Corporation
- Northern California Institute for Research and Education
- Eisai
- Servier
- H. Lundbeck A/S
- IXICO
- National Institutes of Health
- Genentech
- Canadian Institutes of Health Research