The Physical Compatibility of Orphenadrine Citrate with 0.45% Sodium Chloride, Lactated Ringer's Solution, and Plasma-Lyte A.

Orphenadrine citrate is physically compatible with 0.45% NaCl for up to 24 hours. LR and PLA were classified as physically incompatible beyond 1 hour due to significant changes in pH. An evaluation of chemical stability is needed to support these findings.

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PubMed
Published
2025-10-20
Primary Topic
Analytical Methods in Pharmaceuticals
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article
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article

The Physical Compatibility of Orphenadrine Citrate with 0.45% Sodium Chloride, Lactated Ringer's Solution, and Plasma-Lyte A.

Mariann D. Churchwell, Chidimma G. Ezema, Mitchell S. Howard, Justin P. Reinert et al.
PubMed
Analytical Methods in Pharmaceuticals
article

The Physical Compatibility of Orphenadrine Citrate with 0.45% Sodium Chloride, Lactated Ringer's Solution, and Plasma-Lyte A.

Mariann D. Churchwell, Chidimma G. Ezema, Mitchell S. Howard, Justin P. Reinert, Gabriella Baki
article en

Abstract

Orphenadrine citrate is physically compatible with 0.45% NaCl for up to 24 hours. LR and PLA were classified as physically incompatible beyond 1 hour due to significant changes in pH. An evaluation of chemical stability is needed to support these findings.

PubMedVol. 29(5)
University of Toledo (US)
Openalex Percentile: Top 66%
Analytical Methods in Pharmaceuticals
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