Effects of resveratrol on orthodontic tooth movement in Wistar rats: a biochemical, histological and in silico study

Resveratrol exhibits potent antioxidant and anti-inflammatory effects, enhancing bone remodeling and reducing TNF-α-mediated inflammation in OTM. These findings suggest its potential as a therapeutic adjunct in orthodontic treatments to mitigate adverse effects of mechanical forces on bone metabolism.

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Publication Details

Journal
Folia Morphologica
Published
2025-10-16
DOI
https://doi.org/10.5603/fm.105425
Primary Topic
Sirtuins and Resveratrol in Medicine
Type
article
Field-Weighted Citation Impact
0.00
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article

Effects of resveratrol on orthodontic tooth movement in Wistar rats: a biochemical, histological and in silico study

Fırat Aşir, Kamile Keskin Oruç
Folia Morphologica
Sirtuins and Resveratrol in Medicine
article

Effects of resveratrol on orthodontic tooth movement in Wistar rats: a biochemical, histological and in silico study

Fırat Aşir, Kamile Keskin Oruç
article en

Abstract

Resveratrol exhibits potent antioxidant and anti-inflammatory effects, enhancing bone remodeling and reducing TNF-α-mediated inflammation in OTM. These findings suggest its potential as a therapeutic adjunct in orthodontic treatments to mitigate adverse effects of mechanical forces on bone metabolism.

Folia Morphologica
Dicle University (TR)
Openalex Percentile: Top 64%
Sirtuins and Resveratrol in Medicine
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