Quercetin ameliorates nicotine-induced spermatogenesis damage via modulation of sperm miR-151a-5p and testicular Cep72 gene expression

This study demonstrates that quercetin may protect against nicotine-induced testicular damage by maintaining hormonal balance, enhancing AR expression, improving antioxidant enzyme activity, and normalizing the miR-151a-5p/Cep72 regulatory axis, ultimately supporting sperm quality and spermatogenesis. These results establish a foundation for future mechanistic and translational research.