Methylome-driven regulation of miRNA expression and its relationship to cardiac dysfunction in idiopathic dilated cardiomyopathy
This study enhances our understanding of the epigenetic mechanisms shaping the miRNA transcriptomic landscape in iDCM, suggesting potential roles for these miRNAs in cardiac dysfunction and myocardial fibrosis.
Authors
- Lorena Pérez-Carrillo (ORCID: https://orcid.org/0000-0001-8185-0207)
- Manuel Portolés (ORCID: https://orcid.org/0000-0002-4415-7160)
- Esther Roselló‐Lletí (ORCID: https://orcid.org/0000-0003-2627-6104)
- Alex Gallego‐Martínez (ORCID: https://orcid.org/0000-0002-9758-6540)
- Estefanía Tarazón (ORCID: https://orcid.org/0000-0003-3466-2558)
- Marta Delgado‐Arija (ORCID: https://orcid.org/0009-0006-1272-1990)
- Irene González-Torrent
- Carlota Benedicto-Marrero
- Juan Bodí-Miret
Institutions
- Centro de Investigación en Red en Enfermedades Cardiovasculares (ES)
- Centre for Biomedical Network Research on Rare Diseases (ES)
- Medical Research Network (US)
- Instituto de Investigación Sanitaria La Fe (ES)
Publication Details
- Journal
- Clinical Epigenetics
- Published
- 2025-10-22
- DOI
- https://doi.org/10.1186/s13148-025-01989-8
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission
- Ministerio de Ciencia e Innovación
- Centro de Investigación Biomédica en Red Enfermedades Cardiovasculares
- Instituto de Salud Carlos III
- Agencia Estatal de Investigación