Molecular characterization of macrophage-related prognostic factors in glioblastoma revealed by combined analysis on single-cell and bulk transcriptome data
This study reveals the molecular characteristics of key prognostic factors in GBM, highlighting the importance of immune cell abundance and drug sensitivity in glioma treatment, and provides potential biomarkers and therapeutic targets for future clinical research and treatment strategies.
Authors
- Hongchao Liu (ORCID: https://orcid.org/0000-0001-5241-1002)
- Yajun Yang (ORCID: https://orcid.org/0000-0001-9651-8549)
- Zhihao Wei (ORCID: https://orcid.org/0009-0008-4174-9241)
- Mengting Liu (ORCID: https://orcid.org/0000-0001-9813-5939)
Institutions
- Henan University of Science and Technology (CN)
- Luoyang Central Hospital Affiliated to Zhengzhou University (CN)
- First Affiliated Hospital of Henan University of Science and Technology (CN)
- Luoyang Orthopedic-Traumatological Hospital of Henan Province (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-10-22
- DOI
- https://doi.org/10.1007/s12672-025-03816-1
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 0.00