Effect of a patient-specific QTc alert on decreasing prescribing of QTc-prolonging medications in outpatients

This study demonstrated that an interruptive EHR alert at the time of order entry can decrease exposure to QTc-prolonging medications and potentially decrease the risk for ventricular arrhythmias in nonhospitalized patients with a prolonged QTc interval. Further research is needed to determine whether integration of other patient-specific parameters into the CDS alert would improve its potential to lower the risk of QTc-related adverse outcomes.