DNA methylation: a potential mediator between air pollution exposures and asthma control

These findings suggest that air pollution-associated changes in DNA methylation may affect asthma control for some loci, thus help elucidate underlying mechanisms in asthmatic patients. These epigenetic alterations highlight potential targets for understanding the pathophysiology of asthma due to air pollution. While our findings suggest possible links between air pollution, DNA methylation, and asthma control, more evidence is needed to establish causal relationships and unravel the complexities of these connections.