Study on the in vitro and in vivo killing effects of PD-1 antibody-secreting c-Met-targeted CAR-T cells on esophageal cancer cell line ECA109
The c-Met/PD-1 CAR-T cells were successfully constructed and demonstrated significant in vitro and in vivo killing effects on ECA109 esophageal cancer cells.
Authors
- Jingting Min
- Zhenghong Li (ORCID: https://orcid.org/0000-0003-2583-5082)
- Fei Chu (ORCID: https://orcid.org/0000-0002-8887-8349)
- Xiangcheng Zhen
- Haipeng Li (ORCID: https://orcid.org/0000-0002-3244-383X)
- Yanjun Zhang (ORCID: https://orcid.org/0000-0002-9597-2050)
- Yanqiu Li (ORCID: https://orcid.org/0009-0008-8361-7116)
- Shang Peng
- Nana Du (ORCID: https://orcid.org/0009-0003-5713-2784)
- Ran An (ORCID: https://orcid.org/0009-0007-4544-2071)
Institutions
- Bengbu Medical College (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-10-21
- DOI
- https://doi.org/10.1007/s12672-025-03747-x
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Bengbu Medical College