Real-life use of isavuconazole in Spanish children and adolescents

ISA appears to be a safe and effective option for treating IFD in children, especially when first-line agents have failed or caused excessive toxicity. Although no correlation between Ctrough and clinical outcomes was observed, the significant proportion of patients with out-of-range Ctrough emphasizes the need for TDM in paediatrics.

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Publication Details

Journal
Journal of Antimicrobial Chemotherapy
Published
2025-10-08
DOI
https://doi.org/10.1093/jac/dkaf394
Citations
1
Primary Topic
Antifungal resistance and susceptibility
Type
article
Field-Weighted Citation Impact
1.40
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article

Real-life use of isavuconazole in Spanish children and adolescents

Pere Soler‐Palacín, Carlos Grasa, Marta Taida García Ascaso, Ángela Manzanares et al.
1 citations
Journal of Antimicrobial Chemotherapy
Antifungal resistance and susceptibility
1.40
article

Real-life use of isavuconazole in Spanish children and adolescents

Pere Soler‐Palacín, Carlos Grasa, Marta Taida García Ascaso, Ángela Manzanares, Natalia Mendoza‐Palomar, David Díaz Pérez, José Tomás Ramos-Amador, Antoni Noguera‐Julián, Elena María Rincón‐López, Marisa Navarro, Laura Alonso, Silvia Simó Nebot, Begoña Carazo Gallego, Cristina Gato Núñez, Laura Roig-Soria, Beatriz Álvarez Vallejo, Beatriz Jiménez Montero, Clara Izquierdo Anto
article en
1 citations

Abstract

ISA appears to be a safe and effective option for treating IFD in children, especially when first-line agents have failed or caused excessive toxicity. Although no correlation between Ctrough and clinical outcomes was observed, the significant proportion of patients with out-of-range Ctrough emphasizes the need for TDM in paediatrics.

Journal of Antimicrobial ChemotherapyVol. 81(1)
Universidad Complutense de Madrid (ES), Hospital Sant Joan de Déu Barcelona (ES), Hospital Universitario La Paz (ES), Instituto de Salud Carlos III (ES), Hospital General Universitario Gregorio Marañón (ES), Research Institute Hospital 12 de Octubre (ES), Departament de Salut (ES), Marqués de Valdecilla University Hospital (ES), Vall d'Hebron Institut de Recerca (ES), Hospital La Paz Institute for Health Research (ES), Hospital Regional Universitario de Málaga (ES), Centre for Biomedical Network Research on Rare Diseases (ES), Hospital Infantil Universitario Niño Jesús (ES), Vall d'Hebron Hospital Universitari (ES), Hospital Universitario Virgen de la Arrixaca (ES), Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (ES), Instituto de Investigación de Enfermedades Raras (ES), Medical Research Network (US), Universitat de Barcelona (ES)
Openalex Percentile: Top 15%
Antifungal resistance and susceptibility
1.40
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