A new IRMA module for analyzing whole-genome sequences from human metapneumovirus

The large amount of genetic diversity in human metapneumovirus makes reference-based alignments difficult. We created a new module for the Iterative Refinement Meta-Assembler (IRMA) that performs alignment and consensus sequence generation without requiring subtyping and can handle duplications in the glycoprotein. This module increases the feasibility of genomic surveillance.

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Publication Details

Journal
Microbiology Resource Announcements
Published
2025-10-21
DOI
https://doi.org/10.1128/mra.00901-25
Citations
1
Primary Topic
Respiratory viral infections research
Type
article
Field-Weighted Citation Impact
1.35
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article

A new IRMA module for analyzing whole-genome sequences from human metapneumovirus

Emily E. Bendall, Adam S. Lauring
1 citations
Microbiology Resource Announcements
Respiratory viral infections research
1.35
article

A new IRMA module for analyzing whole-genome sequences from human metapneumovirus

Emily E. Bendall, Adam S. Lauring
article en
1 citations

Abstract

The large amount of genetic diversity in human metapneumovirus makes reference-based alignments difficult. We created a new module for the Iterative Refinement Meta-Assembler (IRMA) that performs alignment and consensus sequence generation without requiring subtyping and can handle duplications in the glycoprotein. This module increases the feasibility of genomic surveillance.

Microbiology Resource AnnouncementsVol. 14(11)
University of Michigan (US)
Openalex Percentile: Top 15%
Respiratory viral infections research
1.35
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