Index Cancer Density Is a Stronger Predictor of Pelvic Lymph Node Invasion than Percentage of Biopsy-Positive Cores in EAU High-Risk Prostate Cancer: Clinical Impact in 254 Patients Treated and Staged with Robot-Assisted Radical Prostatectomy
In the investigated population, Id-BPC was a stronger predictor of PLNI than BPC; accordingly, as Id-BPC increased, patients were more likely to have PLNI; equivalently, subjects presenting with Id-BPC less than one were 3.5 times less likely to have PLNI. This information has implications for clinical practice as well as for computing nomograms or patterns of artificial intelligence networks.
Authors
- Salvatore Siracusano (ORCID: https://orcid.org/0000-0002-1709-9823)
- Alessandro Tafuri (ORCID: https://orcid.org/0000-0003-1404-2925)
- Rossella Orlando
- Riccardo Giuseppe Bertolo (ORCID: https://orcid.org/0000-0003-0260-4601)
- Filippo Migliorini (ORCID: https://orcid.org/0000-0003-4427-7151)
- Alessandro Antonelli (ORCID: https://orcid.org/0000-0002-5211-6342)
- Francesco Artoni (ORCID: https://orcid.org/0009-0003-4937-7597)
- Matteo Brunelli (ORCID: https://orcid.org/0000-0002-3832-2676)
- Antonio Benito Porcaro (ORCID: https://orcid.org/0000-0002-7890-040X)
- Maria Angela Cerruto (ORCID: https://orcid.org/0000-0002-1793-2336)
- Riccardo Rizzetto
- Andrea Panunzio (ORCID: https://orcid.org/0000-0002-9756-4632)
- Lorenzo De Bon
- Francesca Montanaro (ORCID: https://orcid.org/0009-0005-6648-9878)
- Alessandro Veccia (ORCID: https://orcid.org/0000-0001-5947-3206)
- Alberto Baielli
- Alberto Bianchi (ORCID: https://orcid.org/0009-0008-6041-5810)
- Vincenzo De Marco
- Andrea Franceschini
Institutions
- University of Verona (IT)
- University of L'Aquila (IT)
- Azienda Ospedaliera Universitaria Integrata Verona (IT)
- Ospedale Vito Fazzi (IT)
Publication Details
- Journal
- Cancers
- Published
- 2025-10-21
- DOI
- https://doi.org/10.3390/cancers17203385
- Citations
- 1
- Primary Topic
- Prostate Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.52