Long-term Survival and Molecular Biomarker Evaluation of a Phase II Cetuximab and Nivolumab Clinical Trial in Recurrent/Metastatic Head and Neck Cancer
Our long-term follow-up study indicates that the combination of cetuximab and nivolumab is efficacious and tolerable and that patients with p16-negative R/M HNSCC may have greater benefit from this combination.
Authors
- Marcelo Raul Bonomi (ORCID: https://orcid.org/0000-0002-9399-3608)
- Juan C. Hernandez‐Prera (ORCID: https://orcid.org/0000-0003-0809-4649)
- Gad A. Getz (ORCID: https://orcid.org/0000-0002-0936-0753)
- Robbert J.C. Slebos (ORCID: https://orcid.org/0000-0003-3117-9544)
- Antonio L. Amelio (ORCID: https://orcid.org/0000-0002-6295-2694)
- José A. Guevara-Patiño (ORCID: https://orcid.org/0000-0002-6258-7228)
- Christine H. Chung (ORCID: https://orcid.org/0000-0001-5199-4306)
- Aik Choon Tan (ORCID: https://orcid.org/0000-0003-2955-8369)
- James William Rocco (ORCID: https://orcid.org/0000-0001-5312-0303)
- Kedar Kirtane (ORCID: https://orcid.org/0000-0003-1302-9577)
- Nabil F. Saba (ORCID: https://orcid.org/0000-0003-4972-1477)
- Brian P. Danysh (ORCID: https://orcid.org/0000-0001-6839-6337)
- Michael J. Schell (ORCID: https://orcid.org/0000-0003-4594-6601)
- Robin Park (ORCID: https://orcid.org/0000-0002-3004-3285)
- Samuel S. Freeman (ORCID: https://orcid.org/0000-0001-8285-0057)
- Nicholas J. Haradhvala (ORCID: https://orcid.org/0000-0003-1113-3135)
- Ritu Chaudhary (ORCID: https://orcid.org/0009-0007-9417-0340)
- Maria I. Poole (ORCID: https://orcid.org/0009-0004-8006-8036)
- Sowjanya Thatikonda (ORCID: https://orcid.org/0000-0002-5353-7202)
- Jiannong Li
- Yeva Meshkovska
- Xiaofei Song (ORCID: https://orcid.org/0000-0002-6585-7318)
- Graydon Moorhead
Institutions
- Broad Institute (US)
- Memorial Sloan Kettering Cancer Center (US)
- Harvard University (US)
- Emory University (US)
- University of Utah (US)
- The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (US)
- Huntsman Cancer Institute (US)
- The Ohio State University Wexner Medical Center (US)
- Moffitt Cancer Center (US)
- Piedmont Cancer Institute (US)
- Center for Cancer Research (US)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2025-10-21
- DOI
- https://doi.org/10.1158/1078-0432.ccr-25-2201
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00