Association of Tumor-Infiltrating Lymphocyte Subtypes with Clinical Characteristics and Prognosis in Young Women with Hormone Receptor–Positive Breast Cancer
Characterization of immune subpopulations could help refine the prognostic value of TILs in young patients with HR-positive breast cancer, who may benefit from risk stratification for treatment individualization.
Authors
- Virginia F. Borges (ORCID: https://orcid.org/0000-0003-1158-7524)
- Jeffrey M. Peppercorn (ORCID: https://orcid.org/0000-0001-7138-6404)
- Yujing Jan Heng (ORCID: https://orcid.org/0000-0002-8930-817X)
- Shoshana M. Rosenberg (ORCID: https://orcid.org/0000-0002-0074-6385)
- Laura C. Collins (ORCID: https://orcid.org/0000-0001-6751-4792)
- Craig Snow (ORCID: https://orcid.org/0009-0007-1572-4895)
- Yaileen D. Guzmán‐Arocho (ORCID: https://orcid.org/0009-0007-7574-2729)
- Kathryn J. Ruddy (ORCID: https://orcid.org/0000-0001-6298-332X)
- Elizabeth A. Mittendorf (ORCID: https://orcid.org/0000-0002-9762-8536)
- Lidia Schapira (ORCID: https://orcid.org/0000-0003-1431-6543)
- Ann H. Partridge (ORCID: https://orcid.org/0000-0002-4722-4824)
- Rulla M. Tamimi (ORCID: https://orcid.org/0000-0003-2306-8668)
- Steven E. Come (ORCID: https://orcid.org/0000-0001-8136-2908)
- Nabihah Tayob (ORCID: https://orcid.org/0000-0001-6088-167X)
- Megan E. Tesch (ORCID: https://orcid.org/0000-0001-6568-726X)
- Eric P. Winer (ORCID: https://orcid.org/0000-0002-8819-1723)
- Yue Zheng (ORCID: https://orcid.org/0000-0002-2294-813X)
Institutions
- Brigham and Women's Hospital (US)
- Beth Israel Deaconess Medical Center (US)
- Cancer Prevention Institute of California (US)
- Mayo Clinic (US)
- Harvard University (US)
- Cornell University (US)
- Beth Israel Deaconess Hospital (US)
- Harvard University Press (US)
- Yale Cancer Center (US)
- Massachusetts General Hospital (US)
- Dana-Farber Cancer Institute (US)
- Mayo Clinic in Arizona (US)
- University of Colorado Cancer Center (US)
- Dana-Farber/Harvard Cancer Center (US)
- Dana-Farber Brigham Cancer Center (US)
- Weill Cornell Medicine (US)
- University of Colorado Denver (US)
- Stanford University (US)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2025-10-21
- DOI
- https://doi.org/10.1158/1078-0432.ccr-25-0948
- Citations
- 1
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 1.05