N-(2-Fluoro-2-propen-1-yl)-5-(trifluoromethyl)-2-pyridinecarboxamide

Herein, the synthesis and crystallization of the unreported compound N-(2-fluoro-2-propen-1-yl)-5-(trifluoromethyl)-2-pyridinecarboxamide is achieved via amide coupling with a (2-fluoroallyl)ammonium salt. The structural properties are analyzed via single-crystal X-ray crystallography. Hydrogen bonding interactions between the amide groups and pyridine nitrogen atoms create a unique linear array of molecules in the crystal packing diagram. Furthermore, to validate the crystallographic data, the structural features of the compound are evaluated and compared to values reported in the literature.

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Publication Details

Journal
Molbank
Published
2025-10-21
DOI
https://doi.org/10.3390/m2078
Primary Topic
Fluorine in Organic Chemistry
Type
article
Field-Weighted Citation Impact
0.00

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article

N-(2-Fluoro-2-propen-1-yl)-5-(trifluoromethyl)-2-pyridinecarboxamide

Jean‐Denys Hamel, Taylor Semeniuk
Molbank
Fluorine in Organic Chemistry
article

N-(2-Fluoro-2-propen-1-yl)-5-(trifluoromethyl)-2-pyridinecarboxamide

Jean‐Denys Hamel, Taylor Semeniuk
article en

Abstract

Herein, the synthesis and crystallization of the unreported compound N-(2-fluoro-2-propen-1-yl)-5-(trifluoromethyl)-2-pyridinecarboxamide is achieved via amide coupling with a (2-fluoroallyl)ammonium salt. The structural properties are analyzed via single-crystal X-ray crystallography. Hydrogen bonding interactions between the amide groups and pyridine nitrogen atoms create a unique linear array of molecules in the crystal packing diagram. Furthermore, to validate the crystallographic data, the structural features of the compound are evaluated and compared to values reported in the literature.

MolbankVol. 2025(4)
University of Lethbridge (CA)
University of Lethbridge, Canada Research Chairs, Natural Sciences and Engineering Research Council of Canada
Openalex Percentile: Top 77%
Fluorine in Organic Chemistry
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N-(2-Fluoro-2-propen-1-yl)-5-(trifluoromethyl)-2-pyridinecarboxamide — Jean‐Denys Hamel, Taylor Semeniuk · Molbank (2025) | TGRS Research Map | TGRS