Fazekas score predicts cognitive decline & frailty in older adults: insights from the SAGE-AF cohort study
Higher Fazekas scores are related to cognitive decline and frailty in older adults with AF, emphasizing WMH as a critical biomarker for aging-related impairments. Neuroimaging tools like Fazekas scoring could enhance risk stratification and inform targeted interventions for this vulnerable population.
Authors
- Jane S. Saczynski (ORCID: https://orcid.org/0000-0002-6411-4774)
- Bahadar S. Srichawla (ORCID: https://orcid.org/0000-0002-5301-4102)
- Melanie Barbini (ORCID: https://orcid.org/0000-0003-4736-5202)
- David D. McManus (ORCID: https://orcid.org/0000-0002-9343-6203)
- Majaz Moonis (ORCID: https://orcid.org/0000-0002-9747-0003)
- Darleen Lessard (ORCID: https://orcid.org/0000-0002-9644-2203)
Institutions
- Northeastern University (US)
- University of Massachusetts Chan Medical School (US)
Publication Details
- Journal
- Neurological Research and Practice
- Published
- 2025-10-21
- DOI
- https://doi.org/10.1186/s42466-025-00439-3
- Citations
- 1
- Primary Topic
- Frailty in Older Adults
- Type
- article
- Field-Weighted Citation Impact
- 1.22
Funders
- National Institutes of Health