Development and validation of a risk prediction algorithm for high-risk populations combining genetic and conventional risk factors of cardiovascular disease
In a high-risk population, PRS is a strong independent risk factor for CVD and should be considered in routine risk assessment, starting at a relatively young age.
Authors
- Tuuli Jürgenson (ORCID: https://orcid.org/0000-0002-9998-1640)
- Lili Milani (ORCID: https://orcid.org/0000-0002-5323-3102)
- Ave Põld (ORCID: https://orcid.org/0000-0001-8188-4909)
- Krista Fischer (ORCID: https://orcid.org/0000-0002-3521-0599)
- Mikk Jürisson (ORCID: https://orcid.org/0000-0002-4487-7045)
- Aet Elken
Institutions
- Tartu University Hospital (EE)
- North Estonia Medical Centre (EE)
- University of Tartu (EE)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-10-21
- DOI
- https://doi.org/10.1371/journal.pone.0335064
- Citations
- 1
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.82