In Vitro Calcification of Bioprosthetic Heart Valves: Method Validation by Comparative Heart Valve Calcification Testing

We developed and validated a novel and unique test method for in vitro calcification assessment. The quantitative calcification tendencies of the two test groups are comparable with the results of an in vivo study in sheep. The structural findings are in line with published in vivo observations. The histomorphological localization appears as known for porcine prostheses.

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Publication Details

Journal
Artificial Organs
Published
2025-10-21
DOI
https://doi.org/10.1111/aor.70015
Citations
1
Primary Topic
Orthopaedic implants and arthroplasty
Type
article
Field-Weighted Citation Impact
2.01
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article

In Vitro Calcification of Bioprosthetic Heart Valves: Method Validation by Comparative Heart Valve Calcification Testing

L. Peters, Marek Weiler, Ulrich Steinseifer, Thomas Schmitz‐Rode et al.
1 citations
Artificial Organs
Orthopaedic implants and arthroplasty
2.01
article

In Vitro Calcification of Bioprosthetic Heart Valves: Method Validation by Comparative Heart Valve Calcification Testing

L. Peters, Marek Weiler, Ulrich Steinseifer, Thomas Schmitz‐Rode, Nicole Kiesendahl, Christoph Schmitz, Johanna C. Clauser
article en
1 citations

Abstract

We developed and validated a novel and unique test method for in vitro calcification assessment. The quantitative calcification tendencies of the two test groups are comparable with the results of an in vivo study in sheep. The structural findings are in line with published in vivo observations. The histomorphological localization appears as known for porcine prostheses.

Artificial OrgansVol. 50(1)
BioMed X Institute (DE), RWTH Aachen University (DE)
Openalex Percentile: Top 11%
Orthopaedic implants and arthroplasty
2.01
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