The Cannabinoid System as a Potential Novel Target for Alcohol‐Associated Liver Disease: A Propensity‐Matched Cohort Study
In this propensity-matched cohort study of patients with AUD, cannabis use was associated with a reduced risk of ALD, with the greatest risk reduction seen in patients with CUD compared to CU and non-CU. Our findings suggest that modulation of cannabinoid receptors may offer a new target for the development of pharmacological therapies for ALD.
Authors
- Vinay Jahagirdar (ORCID: https://orcid.org/0000-0001-6685-1033)
- Luis Antonio Díaz (ORCID: https://orcid.org/0000-0002-8540-4930)
- Kaanthi Rama (ORCID: https://orcid.org/0000-0002-1691-7812)
- Juan Pablo Arab (ORCID: https://orcid.org/0000-0002-8561-396X)
- David Hudson (ORCID: https://orcid.org/0000-0001-8020-1870)
- Butros Fakhoury (ORCID: https://orcid.org/0000-0001-6909-6328)
- Wei Wang (ORCID: https://orcid.org/0000-0001-9670-1423)
Institutions
- Western University (CA)
- Pontificia Universidad Católica de Chile (CL)
- Virginia Commonwealth University (US)
- London Health Sciences Centre (CA)
- University of California San Diego (US)
- St Mary's Hospital (US)
Publication Details
- Journal
- Liver International
- Published
- 2025-10-21
- DOI
- https://doi.org/10.1111/liv.70401
- Primary Topic
- Cannabis and Cannabinoid Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00