The β integrin modulates serotonin sensitivity via <scp>NPxY</scp> motifs to regulate egg laying and mechanosensation behaviors in <i>Caenorhabditis elegans</i>
Our results underscore the functional importance of pat-3 NPxY motifs in muscle and neurons, potentially linking integrin NPxY motifs to neurotransmitter response and mechanosensory functions.
Authors
- Angela Haeun Choi (ORCID: https://orcid.org/0009-0008-6935-7645)
- Daniel Dogeon Lee
- Josh Haram Bumm
- Lianzijun Wang (ORCID: https://orcid.org/0000-0001-6467-4387)
- Martin Aastrup Olsen (ORCID: https://orcid.org/0000-0001-5196-4588)
- Myeongwoo Lee (ORCID: https://orcid.org/0000-0003-2652-3646)
- Zhongqiang Qiu
- Meghana Kolluri
Institutions
- Baylor University (US)
Publication Details
- Journal
- Developmental Dynamics
- Published
- 2025-10-21
- DOI
- https://doi.org/10.1002/dvdy.70090
- Primary Topic
- Genetics, Aging, and Longevity in Model Organisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00