Population‐Based Molecular Surveillance of Hepatitis B Virus Genotypes in the Goto Islands, Japan: A Three Decade Study (1977–2008) of 916 Carriers
This study presents rare population-based molecular evidence of sustained HBV genotype C2 endemicity and intra-community transmission within a defined setting. The findings underscore clinical significance of implementing targeted area- and population-specific strategies including early detection through screening, linkage to care, vaccination, and long-term surveillance, as an effective model for HBV micro-elimination in high-burden communities.
Authors
- Kazuaki Takahashi (ORCID: https://orcid.org/0000-0003-0419-1927)
- Aya Sugiyama (ORCID: https://orcid.org/0000-0002-8087-4319)
- Ko Ko (ORCID: https://orcid.org/0000-0002-6961-2000)
- Kazuhiro Hirase
- Junko Tanaka (ORCID: https://orcid.org/0000-0002-5669-4051)
- Shingo Fukuma (ORCID: https://orcid.org/0000-0002-8379-8761)
- Satoshi Shirahama
- Tomoyuki Akita (ORCID: https://orcid.org/0000-0002-1056-3611)
- Takahiro Yasaka
- Kazumi Yamasaki
- Golda Akuffo Ataa
Institutions
- Hiroshima University (JP)
- Mizushima Central Hospital (JP)
- Photodigm (United States) (US)
- Nagasaki Medical Center (JP)
- Hiroshima City University (JP)
Publication Details
- Journal
- Hepatology Research
- Published
- 2025-10-21
- DOI
- https://doi.org/10.1111/hepr.70060
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministry of Health, Labour and Welfare
- European Association for the Study of the Liver