The Fluctuation Pattern of Osteogenic Markers in the Periosteum During Autologous Guided Bone Regeneration

This study provides comprehensive insights into the dynamic expression characteristics of osteogenic markers throughout guided bone regeneration processes. The observed differences and fluctuations are most pronounced within the first month postsurgery, underscoring the importance of monitoring molecular expression changes during this critical period. Therefore, ALPL, RUNX2, and SP7 may be more suitable than BGLAP for evaluating efficacious osteogenesis during autologous guided bone regeneration.

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Publication Details

Journal
Journal of Craniofacial Surgery
Published
2025-10-20
DOI
https://doi.org/10.1097/scs.0000000000012104
Primary Topic
Bone Tissue Engineering Materials
Type
article
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article

The Fluctuation Pattern of Osteogenic Markers in the Periosteum During Autologous Guided Bone Regeneration

Bao‐Fu Yu, Chuanchang Dai, Jiao Wei
Journal of Craniofacial Surgery
Bone Tissue Engineering Materials
article

The Fluctuation Pattern of Osteogenic Markers in the Periosteum During Autologous Guided Bone Regeneration

Bao‐Fu Yu, Chuanchang Dai, Jiao Wei
article en

Abstract

This study provides comprehensive insights into the dynamic expression characteristics of osteogenic markers throughout guided bone regeneration processes. The observed differences and fluctuations are most pronounced within the first month postsurgery, underscoring the importance of monitoring molecular expression changes during this critical period. Therefore, ALPL, RUNX2, and SP7 may be more suitable than BGLAP for evaluating efficacious osteogenesis during autologous guided bone regeneration.

Journal of Craniofacial Surgery
International Paper (United States) (US), Shanghai Ninth People's Hospital (CN)
Openalex Percentile: Top 71%
Bone Tissue Engineering Materials
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