Bisphosphonate Therapy for Fibrous Dysplasia of The Jaw in Children

Fibrous dysplasia (FD) is an uncommon genetic disorder in which bone is replaced by immature bony and fibrous tissue, manifesting as slow-growing lesions. The craniofacial area is the most common site of fibrous dysplasia, and 9 out of 10 patients with fibrous dysplasia affecting the craniofacial bones present before the age of 5. This case of monostotic fibrous dysplasia of the mandible in a 06 year old child presented with severe bone pain and trismus. This case report emphasises on medical management of fibrous dysplasia with intravenous zoledronic acid resulting in prompt resolution of sign and symptoms.

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Publication Details

Journal
Journal of Craniofacial Surgery
Published
2025-10-20
DOI
https://doi.org/10.1097/scs.0000000000012037
Primary Topic
Bone Tumor Diagnosis and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Bisphosphonate Therapy for Fibrous Dysplasia of The Jaw in Children

Ajay P. Desai, Sudarshan Bhat, Kapil Tomar, Rasika Gawas et al.
Journal of Craniofacial Surgery
Bone Tumor Diagnosis and Treatments
article

Bisphosphonate Therapy for Fibrous Dysplasia of The Jaw in Children

Ajay P. Desai, Sudarshan Bhat, Kapil Tomar, Rasika Gawas, Paras Kshirsagar, Sonam Deki
article en

Abstract

Fibrous dysplasia (FD) is an uncommon genetic disorder in which bone is replaced by immature bony and fibrous tissue, manifesting as slow-growing lesions. The craniofacial area is the most common site of fibrous dysplasia, and 9 out of 10 patients with fibrous dysplasia affecting the craniofacial bones present before the age of 5. This case of monostotic fibrous dysplasia of the mandible in a 06 year old child presented with severe bone pain and trismus. This case report emphasises on medical management of fibrous dysplasia with intravenous zoledronic acid resulting in prompt resolution of sign and symptoms.

Journal of Craniofacial Surgery
Armed Forces Medical College (IN)
Openalex Percentile: Top 57%
Bone Tumor Diagnosis and Treatments
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