Insulin Sensitivity and Associated Plasma Proteomics During Sex Hormone Therapy
Feminizing hormone therapy, characterized by high serum estradiol and low serum testosterone concentrations, enhanced insulin sensitivity. These findings highlight the impact of sex hormones on insulin sensitivity and may inform sex-specific precision medicine.
Authors
- Natalie Nokoff (ORCID: https://orcid.org/0000-0002-9190-3947)
- Laura Pyle
- Ye Ji Choi (ORCID: https://orcid.org/0000-0002-0167-175X)
- Phoom Narongkiatikhun (ORCID: https://orcid.org/0000-0002-1569-4581)
- Petter Bjornstad (ORCID: https://orcid.org/0000-0002-5160-2947)
- Irene G. M. van Valkengoed (ORCID: https://orcid.org/0000-0002-9306-7831)
- Sarah E. Siegelaar (ORCID: https://orcid.org/0000-0002-6928-8984)
- Daniël H. van Raalte (ORCID: https://orcid.org/0000-0003-2894-6124)
- Martin den Heijer (ORCID: https://orcid.org/0000-0003-3620-5617)
- Sarah A van Eeghen (ORCID: https://orcid.org/0009-0007-5044-3431)
- Taryn G Vosters (ORCID: https://orcid.org/0009-0009-9712-3894)
Institutions
- University of Washington (US)
- Amsterdam Neuroscience (NL)
- Amsterdam University Medical Centers (NL)
- Chiang Mai University (TH)
- Amsterdam University of Applied Sciences (NL)
- Vrije Universiteit Amsterdam (NL)
- University of Amsterdam (NL)
- Amsterdam UMC Location Vrije Universiteit Amsterdam (NL)
- University of Colorado Denver (US)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2025-10-21
- DOI
- https://doi.org/10.1210/clinem/dgaf573
- Citations
- 1
- Primary Topic
- Hormonal and reproductive studies
- Type
- article
- Field-Weighted Citation Impact
- 1.29