Lysine acetyltransferase 2A-mediated succinylation of adenosine monophosphate-activated protein kinase suppresses gallstone formation by inhibiting inflammation and pyroptosis
KAT2A-mediated succinylation of AMPK inhibited cholelithiasis progression by modulating the AMPK/SIRT1 signaling pathway, offering potential therapeutic strategies for this condition.
Authors
- Mingze Ma (ORCID: https://orcid.org/0000-0002-6706-7483)
- Ruxin Gao (ORCID: https://orcid.org/0009-0006-0596-4898)
- Chuan Qin (ORCID: https://orcid.org/0000-0002-6261-1232)
- Xinxing Wang (ORCID: https://orcid.org/0000-0002-1581-4846)
- Shuai Shao (ORCID: https://orcid.org/0000-0002-8694-9166)
- Lei Zhu (ORCID: https://orcid.org/0000-0002-1820-4795)
- Lu Dai (ORCID: https://orcid.org/0000-0002-6818-8535)
- Zhen-Hai Zhang
- Xianhui Xu
Institutions
- Shandong Provincial Hospital (CN)
Publication Details
- Journal
- World Journal of Gastroenterology
- Published
- 2025-10-21
- DOI
- https://doi.org/10.3748/wjg.v31.i39.110115
- Citations
- 2
- Primary Topic
- Peptidase Inhibition and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 2.09