Clinical impact of multidrug-resistant organisms in liver cirrhosis: A retrospective cohort study in the intensive care setting
MDRO colonization at ICU admission is frequent among critically ill patients with cirrhosis, particularly those with acute-on-chronic liver failure. While colonization alone does not predict infection or early mortality, its clinical value emerges in guiding empirical antibiotic treatment once infection is suspected. Ultimately, short-term survival appears to be more strongly influenced by the severity of organ failure than by either MDRO colonization or infection.
Authors
- Viktor Domislović (ORCID: https://orcid.org/0000-0002-3715-5730)
- Jakša Babel (ORCID: https://orcid.org/0000-0001-8405-2737)
- Anna Mrzljak (ORCID: https://orcid.org/0000-0001-6270-2305)
- Dijana Varda Brkić
- Ivana Mareković (ORCID: https://orcid.org/0000-0002-3471-4285)
- Radovan Radonić (ORCID: https://orcid.org/0000-0002-3147-9160)
- Iva Košuta (ORCID: https://orcid.org/0000-0002-1342-8722)
- Frano Šušak (ORCID: https://orcid.org/0000-0002-3866-2814)
- Laura Peretin
Institutions
- University of Zagreb (HR)
Publication Details
- Journal
- World Journal of Gastroenterology
- Published
- 2025-10-21
- DOI
- https://doi.org/10.3748/wjg.v31.i39.111261
- Citations
- 3
- Primary Topic
- Liver Disease and Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 3.97