Retrospective cohort study of Gram-negative bacteraemia shows transmission of hypervirulent Klebsiella pneumoniae in a UK Intensive Care Unit during the Covid-19 pandemic

Hypervirulent <i>K. pneumoniae</i> is an emerging problem, capable of causing a severe, disseminated infection. We suggest risk factors for transmission may include shared equipment, environmental and PPE contamination, and failure of effective hand hygiene. With COVID-19 infection endemic, if SARS-CoV-2 patients require cohort nursing in bays with sessional use gowns, we recommend these are short-sleeved, to facilitate effective hand hygiene. We argue strict Infection Control policy, including enhanced cleaning, is critical to reduce transmission of hypervirulent <i>K. pneumoniae</i> and advocate for enhanced national surveillance systems.

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Publication Details

Journal
Infection Prevention in Practice
Published
2025-10-21
DOI
https://doi.org/10.1016/j.infpip.2025.100492
Primary Topic
Antibiotic Resistance in Bacteria
Type
article
Field-Weighted Citation Impact
0.00
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article

Retrospective cohort study of Gram-negative bacteraemia shows transmission of hypervirulent Klebsiella pneumoniae in a UK Intensive Care Unit during the Covid-19 pandemic

Olly Allen, Sumita Pai, Rachel Bousfield, R Kappeler et al.
Infection Prevention in Practice
Antibiotic Resistance in Bacteria
article

Retrospective cohort study of Gram-negative bacteraemia shows transmission of hypervirulent Klebsiella pneumoniae in a UK Intensive Care Unit during the Covid-19 pandemic

Olly Allen, Sumita Pai, Rachel Bousfield, R Kappeler, K.J. Randall, J. V. Keane, Stephen Baker
article en

Abstract

Hypervirulent <i>K. pneumoniae</i> is an emerging problem, capable of causing a severe, disseminated infection. We suggest risk factors for transmission may include shared equipment, environmental and PPE contamination, and failure of effective hand hygiene. With COVID-19 infection endemic, if SARS-CoV-2 patients require cohort nursing in bays with sessional use gowns, we recommend these are short-sleeved, to facilitate effective hand hygiene. We argue strict Infection Control policy, including enhanced cleaning, is critical to reduce transmission of hypervirulent <i>K. pneumoniae</i> and advocate for enhanced national surveillance systems.

Infection Prevention in PracticeVol. 7(4)
University of Cambridge (GB), Cambridge University Hospitals NHS Foundation Trust (GB), Bridge University (SS), Papworth Hospital NHS Foundation Trust (GB), Institute of Molecular and Cell Biology (SG)
Openalex Percentile: Top 75%
Antibiotic Resistance in Bacteria
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Retrospective cohort study of Gram-negative bacteraemia shows transmission of hypervirulent Klebsiella pneumoniae in a UK Intensive Care Unit during the Covid-19 pandemic — Olly Allen, Sumita Pai, et al. · Infection Prevention in Practice (2025) | TGRS Research Map | TGRS