Retrospective cohort study of Gram-negative bacteraemia shows transmission of hypervirulent Klebsiella pneumoniae in a UK Intensive Care Unit during the Covid-19 pandemic
Hypervirulent <i>K. pneumoniae</i> is an emerging problem, capable of causing a severe, disseminated infection. We suggest risk factors for transmission may include shared equipment, environmental and PPE contamination, and failure of effective hand hygiene. With COVID-19 infection endemic, if SARS-CoV-2 patients require cohort nursing in bays with sessional use gowns, we recommend these are short-sleeved, to facilitate effective hand hygiene. We argue strict Infection Control policy, including enhanced cleaning, is critical to reduce transmission of hypervirulent <i>K. pneumoniae</i> and advocate for enhanced national surveillance systems.
Authors
- Olly Allen
- Sumita Pai
- Rachel Bousfield (ORCID: https://orcid.org/0000-0001-7828-4048)
- R Kappeler
- K.J. Randall
- J. V. Keane (ORCID: https://orcid.org/0000-0002-2021-1863)
- Stephen Baker
Institutions
- University of Cambridge (GB)
- Cambridge University Hospitals NHS Foundation Trust (GB)
- Bridge University (SS)
- Papworth Hospital NHS Foundation Trust (GB)
- Institute of Molecular and Cell Biology (SG)
Publication Details
- Journal
- Infection Prevention in Practice
- Published
- 2025-10-21
- DOI
- https://doi.org/10.1016/j.infpip.2025.100492
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00