The skin hydration and anti‐ageing benefits of Ectoine, achieved through enhanced Src‐ERK‐mediated HAS‐2 and JNK‐driven AQP‐3 expression in human keratinocytes, along with the inhibition of MMP‐1‐induced collagen‐I degradation in human fibroblasts, b
We demonstrated that Ectoine exerts skin hydration effects without or with UVB exposure in human skin keratinocyte (HaCaT) cells and anti-ageing in fibroblast (Hs68) cells. Therefore, Ectoine could serve as a potential natural compound in cosmetic preparations for skin hydration and anti-ageing.
Authors
- You‐Cheng Hseu (ORCID: https://orcid.org/0000-0001-5307-6162)
- Po‐Yuan Wu (ORCID: https://orcid.org/0000-0003-0264-2536)
- Hsin‐Ling Yang (ORCID: https://orcid.org/0000-0002-3561-7372)
- Sudhir Pandey (ORCID: https://orcid.org/0000-0002-6663-9056)
- Ying‐Ru Chen
- Siang‐Jyun Chen
- Jhih‐Hsuan Hseu
Institutions
- Asia University (TW)
- Chang Gung University (TW)
- China Medical University (TW)
- Kaohsiung Chang Gung Memorial Hospital (TW)
- China Medical University Hospital (TW)
Publication Details
- Journal
- International Journal of Cosmetic Science
- Published
- 2025-10-20
- DOI
- https://doi.org/10.1111/ics.70036
- Primary Topic
- Skin Protection and Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.00