Integrated multi-omics analysis reveals the mechanisms of naringin in ameliorating high-fat diet-induced metabolic dysfunction-associated steatotic liver disease

Our findings indicate that Nar prevents MASLD by harmonizing hepatic lipid metabolism and modulating the gut microbiome, providing a multifaceted mechanistic insight into its therapeutic potential.

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Publication Details

Journal
Frontiers in Nutrition
Published
2025-10-21
DOI
https://doi.org/10.3389/fnut.2025.1694191
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Integrated multi-omics analysis reveals the mechanisms of naringin in ameliorating high-fat diet-induced metabolic dysfunction-associated steatotic liver disease

Na Xue, Qiang Zhang, Wenping Sun
Frontiers in Nutrition
Liver Disease Diagnosis and Treatment
article

Integrated multi-omics analysis reveals the mechanisms of naringin in ameliorating high-fat diet-induced metabolic dysfunction-associated steatotic liver disease

Na Xue, Qiang Zhang, Wenping Sun
article en

Abstract

Our findings indicate that Nar prevents MASLD by harmonizing hepatic lipid metabolism and modulating the gut microbiome, providing a multifaceted mechanistic insight into its therapeutic potential.

Frontiers in NutritionVol. 12
Gansu University of Traditional Chinese Medicine (CN), Gansu Provincial Hospital (CN)
Openalex Percentile: Top 60%
Liver Disease Diagnosis and Treatment
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