Colonoscopy outcomes of primary screening negative participants highlight the missed diagnosis problem of colorectal cancer screening: an observational study from Yuexiu district in Guangzhou, China
Subjects with negative primary screening results but having active screening willingness should consider an earlier colonoscopy due to HRFQ's limited risk predictive ability for colorectal lesions, highlighting an urgency in re-assessment and improvement of the CRC risk scoring system.
Authors
- Chenghua Gong
- Kunhao Bai (ORCID: https://orcid.org/0000-0003-1184-7576)
- Z. G. Yao (ORCID: https://orcid.org/0000-0002-9371-3266)
- Qingjian Ou (ORCID: https://orcid.org/0000-0002-6881-8680)
- Meiying Lu
- Meixian Ye
- Paul W. Bible (ORCID: https://orcid.org/0000-0001-9969-4492)
- Zhenhai Lu
- Yu Liu (ORCID: https://orcid.org/0000-0002-5263-9610)
- Shuang Wang (ORCID: https://orcid.org/0000-0003-3879-9519)
- Jiali Chen (ORCID: https://orcid.org/0000-0002-2692-8179)
- Yahui Xu
- Yanping Wu (ORCID: https://orcid.org/0000-0001-8455-3574)
- Desen Wan
- Yujing Fang
- Zhizhong Pan (ORCID: https://orcid.org/0000-0002-5198-2919)
Institutions
- Guangzhou University of Chinese Medicine (CN)
- DePauw University (US)
- Sun Yat-sen University (CN)
- Guangzhou Center for Disease Control and Prevention (CN)
- HKU-Pasteur Research Pole (HK)
- Sun Yat-sen University Cancer Center (CN)
- Imperial College London (GB)
- University of Hong Kong (HK)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-10-21
- DOI
- https://doi.org/10.3389/fonc.2025.1642326
- Primary Topic
- Colorectal Cancer Screening and Detection
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Guangzhou University of Chinese Medicine
- Guangzhou University
- Health Medical Collaborative Innovation Program of Guangzhou