Subchondral insufficiency fracture of the knee: progress in the pathogenesis and treatment
Subchondral Insufficiency Fracture of the Knee (SIFK) is a disease with unclear pathogenesis and rapid progression, it is prone to developing end-stage osteoarthritis. Due to the lack of a definitive treatment strategy for SIFK in the clinic, knee replacement is often the preferred measure. However, in recent years, as the disease has become better understood, more and more effective treatments have been proposed, but there is a lack of summarization. Therefore, this article summarizes its pathogenesis and therapeutic advances.
Authors
- Bangjian He (ORCID: https://orcid.org/0000-0002-7853-813X)
- Ziyue Wang
- Hang Pei
- Jiale Yuan (ORCID: https://orcid.org/0000-0002-9475-1192)
- Yi Zhang (ORCID: https://orcid.org/0000-0003-3625-2288)
- Chao Wang (ORCID: https://orcid.org/0000-0001-7722-1782)
Institutions
- Zhejiang Chinese Medical University (CN)
- Ningbo No. 2 Hospital (CN)
- County Hospital (GB)
- Ningbo No.6 Hospital (CN)
Publication Details
- Journal
- Frontiers in Surgery
- Published
- 2025-10-21
- DOI
- https://doi.org/10.3389/fsurg.2025.1640316
- Primary Topic
- Bone and Joint Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China