Thioflavonols as potent α-glucosidase inhibitors: <i>in vitro</i> , <i>in vivo</i> , and computational analysis
This is the first comprehensive study of thioflavonols as α-glucosidase inhibitors, demonstrating their promising biological activity, stable binding behavior, and favorable pharmacokinetic properties, supporting their potential as novel anti-diabetic agents.
Authors
- Amina Sadiq
- Abdullah Yahya Abdullah Alzahrani (ORCID: https://orcid.org/0000-0001-5231-8932)
- Mohamed I. A. Othman (ORCID: https://orcid.org/0000-0002-0405-8918)
- Nafeesa Naeem (ORCID: https://orcid.org/0000-0002-6647-9697)
- Bushra Shakoor
- Ehsan Ullah Mughal (ORCID: https://orcid.org/0000-0001-9463-9398)
- Muhammad Zafar (ORCID: https://orcid.org/0000-0003-2002-3907)
Institutions
- Quaid-i-Azam University (PK)
- Government College Women University Faisalabad (PK)
- Government College Women University Sialkot
- King Khalid University (SA)
- University of Gujrat (PK)
Publication Details
- Journal
- Future Medicinal Chemistry
- Published
- 2025-10-21
- DOI
- https://doi.org/10.1080/17568919.2025.2575746
- Citations
- 1
- Primary Topic
- Carbohydrate Chemistry and Synthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.94