MiR-18b-3p promotes cell proliferation and metastasis by directly inhibiting PTEN expression in osteosarcoma
Our findings establish miR-18b-3p as a novel oncogenic regulator in OS pathogenesis through direct PTEN targeting, highlighting its potential as a therapeutic target.
Authors
- Zhun Cao (ORCID: https://orcid.org/0000-0002-7904-2523)
- Huanxiang Bao
- Guoyou Zou (ORCID: https://orcid.org/0000-0002-9099-6168)
- Xiaofei Shen (ORCID: https://orcid.org/0000-0001-6862-634X)
Institutions
- Nantong University (CN)
- Yancheng First People's Hospital (CN)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2025-10-21
- DOI
- https://doi.org/10.1186/s13018-025-06307-9
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00