Multiple primary malignant neoplasms and long‑term survival: A case report
At present, morbidity rates in patients with multiple primary malignant neoplasms (MPMNs) are continually improving as tumor diagnosis and treatment technology progress. The present study aimed to describe the rare case of a patient with MPMNs. Following initial detection of the first primary malignant tumor, the patient underwent six surgical interventions. The medical history showed that the patient had been sequentially diagnosed with seven types of primary tumors over a period of 38 years. These included sigmoid colon cancer, thyroid cancer, ileocecal adenocarcinoma, left lung invasive adenocarcinoma, bilateral breast invasive cancer and right lung invasive adenocarcinoma. Although this clinical presentation of MPMN is exceptionally uncommon, timely detection and consistent medical interventions have led to an increased survival period for affected patients. Therefore, the present study aimed to describe the diagnostic and therapeutic strategies used for the current patient, and to offer novel insights for the clinical management of similar conditions.
Authors
- Ke Huang (ORCID: https://orcid.org/0000-0002-8257-5558)
- Shui-Bo Zhu (ORCID: https://orcid.org/0000-0003-2069-7338)
- Biao Xie
Institutions
- Central Hospital of Wuhan (CN)
- Wuhan General Hospital of Guangzhou (CN)
Publication Details
- Journal
- Oncology Letters
- Published
- 2025-10-21
- DOI
- https://doi.org/10.3892/ol.2025.15351
- Primary Topic
- Multiple and Secondary Primary Cancers
- Type
- article
- Field-Weighted Citation Impact
- 0.00