Efficacy of Thoracic Duct Embolization in Managing Severe Refractory Chyle Leak Post-cervical Reconstruction in a Patient With Liver Cirrhosis: A Case Report

This case report describes a patient with a history of liver cirrhosis who underwent neck reconstruction surgery and subsequently experienced substantial chyle leakage, reaching volumes of up to 6,620 mL per day. Conservative interventions such as fasting, a low-fat diet, total parenteral nutrition, drainage management, somatostatin analogs, and factor XIII supplementation proved ineffective, and the patient exhibited a refractory treatment course. The pronounced chyle leakage in this instance was hypothesized to be linked to increased lymph production resulting from portal hypertension associated with liver cirrhosis. Given the resistance to conservative treatment, thoracic duct embolization was performed by the interventional radiology department, effectively controlling the chyle leakage. The patient experienced a favorable clinical trajectory, devoid of complications. These findings indicate that thoracic duct embolization is a safe and efficacious minimally invasive treatment for refractory and massive chyle leakage following neck dissection and may represent a promising alternative before surgical intervention.

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Journal
Cureus
Published
2025-10-21
DOI
https://doi.org/10.7759/cureus.95040
Primary Topic
Lymphatic Disorders and Treatments
Type
article
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0.00
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article

Efficacy of Thoracic Duct Embolization in Managing Severe Refractory Chyle Leak Post-cervical Reconstruction in a Patient With Liver Cirrhosis: A Case Report

Hiromi Kojima, Hirokazu Ashida, Norio Fukuda, Masato Nagaoka et al.
Cureus
Lymphatic Disorders and Treatments
article

Efficacy of Thoracic Duct Embolization in Managing Severe Refractory Chyle Leak Post-cervical Reconstruction in a Patient With Liver Cirrhosis: A Case Report

Hiromi Kojima, Hirokazu Ashida, Norio Fukuda, Masato Nagaoka, Katsuhiro Ishida
article en

Abstract

This case report describes a patient with a history of liver cirrhosis who underwent neck reconstruction surgery and subsequently experienced substantial chyle leakage, reaching volumes of up to 6,620 mL per day. Conservative interventions such as fasting, a low-fat diet, total parenteral nutrition, drainage management, somatostatin analogs, and factor XIII supplementation proved ineffective, and the patient exhibited a refractory treatment course. The pronounced chyle leakage in this instance was hypothesized to be linked to increased lymph production resulting from portal hypertension associated with liver cirrhosis. Given the resistance to conservative treatment, thoracic duct embolization was performed by the interventional radiology department, effectively controlling the chyle leakage. The patient experienced a favorable clinical trajectory, devoid of complications. These findings indicate that thoracic duct embolization is a safe and efficacious minimally invasive treatment for refractory and massive chyle leakage following neck dissection and may represent a promising alternative before surgical intervention.

CureusVol. 17(10)
Jikei University School of Medicine (JP)
Openalex Percentile: Top 53%
Lymphatic Disorders and Treatments
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Efficacy of Thoracic Duct Embolization in Managing Severe Refractory Chyle Leak Post-cervical Reconstruction in a Patient With Liver Cirrhosis: A Case Report — Hiromi Kojima, Hirokazu Ashida, et al. · Cureus (2025) | TGRS Research Map | TGRS