TLR2 c.374C>T variant linked to natural resistance against brucellosis in Italian Mediterranean river buffalo
This study highlights how TLRs genetic variations may influence protein activity and resistance to brucellosis. The genotyping analysis combined with in silico investigation could be considered an efficient approach for detecting possible candidate marker of resistance to buffalo brucellosis.
Authors
- Alfredo Pauciullo
- Valentina Iovane (ORCID: https://orcid.org/0000-0002-0021-5920)
- Andrea Fulgione (ORCID: https://orcid.org/0000-0002-8646-5073)
- Angela Michela Immacolata Montone (ORCID: https://orcid.org/0000-0001-6097-8500)
- V. Peretti
- Antonio Gentile (ORCID: https://orcid.org/0000-0001-6861-4234)
- Rosanna Capparelli
Institutions
- Federico II University Hospital (IT)
- Istituto Zooprofilattico Sperimentale del Mezzogiorno (IT)
- Department of Agricultural Sciences (RU)
- University of Turin (IT)
- University of Naples Federico II (IT)
Publication Details
- Journal
- BMC Veterinary Research
- Published
- 2025-10-21
- DOI
- https://doi.org/10.1186/s12917-025-05067-2
- Citations
- 1
- Primary Topic
- Brucella: diagnosis, epidemiology, treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.35