E3 ubiquitin ligase BTRC inhibits the proliferation and tumor growth of glioma cells through the NFAT5/AQP4 axis
BTRC negatively modulates the transcription of AQP4 via NFAT5 in glioma cells, thereby influencing their malignant biological functions and tumor growth.
Authors
- Kaiyuan Jiang (ORCID: https://orcid.org/0000-0003-2249-6505)
- Xiqi Hu (ORCID: https://orcid.org/0000-0002-8814-8944)
- Peng Deng (ORCID: https://orcid.org/0000-0001-5781-090X)
- Yexin Li (ORCID: https://orcid.org/0000-0001-5907-8978)
- Siqiang Tang
Institutions
- Hainan General Hospital (CN)
- The Central Hospital of Shaoyang (CN)
Publication Details
- Journal
- Journal of Cancer Research and Clinical Oncology
- Published
- 2025-10-21
- DOI
- https://doi.org/10.1007/s00432-025-06346-z
- Primary Topic
- Ubiquitin and proteasome pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00