Hidden risk factors for recurrence of jejunoileal Gastrointestinal stromal tumors with low NIH classification: implications for surveillance and adjuvant therapy
Jejunoileal GISTs have a significant risk of recurrence despite their low-risk NIH classification. Tumor size, mitotic count, Ki-67 index, and anatomical location should be incorporated into refined risk models to guide follow-up and treatment decisions.
Authors
- Yihong Sun (ORCID: https://orcid.org/0000-0003-3779-1953)
- Ran Xiong (ORCID: https://orcid.org/0000-0002-3512-8851)
- Kuntang Shen (ORCID: https://orcid.org/0000-0002-9600-6508)
- Yuning Zhou (ORCID: https://orcid.org/0000-0001-8173-1718)
- Ping Shu
- Xiaodong Gao (ORCID: https://orcid.org/0000-0003-0119-2334)
- Xiangfei Sun (ORCID: https://orcid.org/0000-0001-6020-7925)
- Yingyong Hou
Institutions
- Fudan University (CN)
- Zhongshan Hospital (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-10-21
- DOI
- https://doi.org/10.1186/s12967-025-07163-1
- Primary Topic
- Gastrointestinal Tumor Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China