TAM family kinases are potential candidate targets for therapeutic intervention in chronic myeloid leukemia
TAM family kinase inhibitors significantly reduce the proliferation and colony formation of K562-S and K562-R cells by inducing apoptosis, interfering with Wnt/β catenin pathway, and upregulating cell cycle inhibitors.
Authors
- Dilawar Khan (ORCID: https://orcid.org/0000-0001-5872-267X)
- Maryam Yousaf (ORCID: https://orcid.org/0000-0003-4113-9052)
- K Arif
Institutions
- National University of Sciences and Technology (PK)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-10-21
- DOI
- https://doi.org/10.1007/s12672-025-03632-7
- Citations
- 1
- Primary Topic
- Chronic Myeloid Leukemia Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.77