Diagnostic performance of a 250-ml net ultrafiltration challenge to identify risk of preload-dependence in critically ill patients undergoing continuous renal replacement therapy: a randomized, cross-over trial
A 250-ml UF<sub>NET</sub> challenge had acceptable diagnostic performance to identify preload-independent patients becoming preload-dependent during CRRT, with no detectable difference between fast and slow challenges. A CCI variation ≥ 5% during a PM in preload-independent patients may help identify those at risk of becoming preload-dependent.
Authors
- Charlotte Biscarrat
- Mehdi Mezidi (ORCID: https://orcid.org/0000-0002-8715-8323)
- Louis Chauvelot (ORCID: https://orcid.org/0000-0001-5995-7921)
- Laurent Bitker (ORCID: https://orcid.org/0000-0002-4698-053X)
- Guillaume Deniel (ORCID: https://orcid.org/0000-0002-4006-6114)
- Jean-Christophe Richard (ORCID: https://orcid.org/0000-0003-1503-3035)
- Hodane Yonis
- Matthieu Chivot
Institutions
- Université Claude Bernard Lyon 1 (FR)
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Lyon College (US)
- Hôpital de la Croix-Rousse (FR)
- Institut National des Sciences Appliquées de Lyon (FR)
Publication Details
- Journal
- Critical Care
- Published
- 2025-10-21
- DOI
- https://doi.org/10.1186/s13054-025-05674-3
- Citations
- 1
- Primary Topic
- Hemodynamic Monitoring and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- Hospices Civils de Lyon