Ten-year outcomes of antiretroviral therapy: a retrospective cohort study in Tshwane district, South Africa

A decade after initiation, fewer than half remained in care. Mortality clustered among older adults and those presenting with advanced disease, while CHC-based care conferred survival and immunologic advantages. Programme priorities should include earlier diagnosis and ART start, youth-friendly retention strategies, and scaling CHC-style differentiated service delivery to improve long-term outcomes.

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Publication Details

Journal
AIDS Research and Therapy
Published
2025-10-21
DOI
https://doi.org/10.1186/s12981-025-00814-9
Primary Topic
HIV/AIDS Research and Interventions
Type
article
Field-Weighted Citation Impact
0.00

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article

Ten-year outcomes of antiretroviral therapy: a retrospective cohort study in Tshwane district, South Africa

Murray Louw, Sanele Ngcobo, Kateko Mhlongo
AIDS Research and Therapy
HIV/AIDS Research and Interventions
article

Ten-year outcomes of antiretroviral therapy: a retrospective cohort study in Tshwane district, South Africa

Murray Louw, Sanele Ngcobo, Kateko Mhlongo
article en

Abstract

A decade after initiation, fewer than half remained in care. Mortality clustered among older adults and those presenting with advanced disease, while CHC-based care conferred survival and immunologic advantages. Programme priorities should include earlier diagnosis and ART start, youth-friendly retention strategies, and scaling CHC-style differentiated service delivery to improve long-term outcomes.

AIDS Research and TherapyVol. 22(1)
University of Pretoria (ZA)
University of Pretoria
Openalex Percentile: Top 65%
HIV/AIDS Research and Interventions
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