The nomenclature of fatty liver disease and its impact on obesity traits, insulin resistance, and hepatic fibrosis
The nomenclature of MAFLD covers a wider range of FLD than NAFLD and MASLD do, but the heterogeneity of AFLD is nonnegligible. Compared with MASLD, NAFLD remains a practical and efficient definition for large-scale population screening, especially in resource-limited settings. TyG-BMI, TyG-WHtR, and TyG-WC could better predict FLD and associated fibrosis, affirming their potential as simple and cost-effective tools to support health monitoring and early intervention.
Authors
- Ruimei Feng (ORCID: https://orcid.org/0000-0001-8020-2654)
- Long He (ORCID: https://orcid.org/0000-0002-6913-220X)
- Liangguang Xiang
- Weimin Ye (ORCID: https://orcid.org/0000-0002-6859-4648)
- Xiaoyun Li (ORCID: https://orcid.org/0000-0003-4732-8073)
- Shanshan Du (ORCID: https://orcid.org/0000-0002-0485-9029)
- Wanxin Li (ORCID: https://orcid.org/0000-0001-7513-7368)
- Jun Chen (ORCID: https://orcid.org/0000-0001-5049-5759)
- Jiamin Gong (ORCID: https://orcid.org/0009-0001-1632-1242)
Institutions
- Fujian Medical University (CN)
- Shanxi Medical University (CN)
- Karolinska Institutet (SE)
Publication Details
- Journal
- Lipids in Health and Disease
- Published
- 2025-10-21
- DOI
- https://doi.org/10.1186/s12944-025-02736-x
- Citations
- 2
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- Natural Science Foundation of Fujian Province
- Fujian Medical University