MicroRNA expression dynamics in mouse liver at different stages of Echinococcus multilocularis infection

Overall, our investigation elucidates the temporal dynamic changes in host miRNAs and their potential target genes at the early, middle and late stages of E. multilocularis infection, which allows us to understand the roles of miRNAs in host-parasite interactions throughout infection and provides a reference for further studies of molecular pathogenesis and new drug or vaccine targets for control of AE.

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Publication Details

Journal
BMC Genomics
Published
2025-10-21
DOI
https://doi.org/10.1186/s12864-025-12049-z
Primary Topic
Parasitic infections in humans and animals
Type
article
Field-Weighted Citation Impact
0.00

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article

MicroRNA expression dynamics in mouse liver at different stages of Echinococcus multilocularis infection

Zheng Feng, Xiaojin Mo, Wei Hu, Ying Chen et al.
BMC Genomics
Parasitic infections in humans and animals
article

MicroRNA expression dynamics in mouse liver at different stages of Echinococcus multilocularis infection

Zheng Feng, Xiaojin Mo, Wei Hu, Ying Chen, Li‐Qun Chen, Ting Zhang, Haijun Gao, Guanghui Zheng, Jun Xie, Bolor Bold, Jie Gao
article en

Abstract

Overall, our investigation elucidates the temporal dynamic changes in host miRNAs and their potential target genes at the early, middle and late stages of E. multilocularis infection, which allows us to understand the roles of miRNAs in host-parasite interactions throughout infection and provides a reference for further studies of molecular pathogenesis and new drug or vaccine targets for control of AE.

BMC GenomicsVol. 26(1)
National Institute for Parasitic Diseases (CN), Shanghai Jiao Tong University (CN), Fudan University (CN), Inner Mongolia University (CN), Ministry of Education (KR), Tibet Autonomous Region People's Hospital (CN)
National Key Research and Development Program of China
Openalex Percentile: Top 58%
Parasitic infections in humans and animals
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MicroRNA expression dynamics in mouse liver at different stages of Echinococcus multilocularis infection — Zheng Feng, Xiaojin Mo, et al. · BMC Genomics (2025) | TGRS Research Map | TGRS