Synergistic protective effects of remote ischemic postconditioning and enalapril on endothelial dysfunction in spontaneously hypertensive rats via inhibition of oxidative stress-mediated mitochondrial dysfunction
RIPost combined with Enalapril synergistically attenuates hypertension-induced vascular injury by reducing inflammation and oxidative stress while preserving mitochondrial function. These findings support the combined therapeutic strategy as a promising approach for comprehensive management of hypertensive vascular complications.
Authors
- Peng Qu (ORCID: https://orcid.org/0000-0001-5339-8946)
- Wanfu Cui (ORCID: https://orcid.org/0009-0000-5929-0696)
- Michael Gao (ORCID: https://orcid.org/0000-0003-0534-4403)
- Qinglei Zhong
- Xinzhu Tong (ORCID: https://orcid.org/0009-0005-1112-0037)
- Dan Rong (ORCID: https://orcid.org/0000-0002-0680-8735)
Institutions
- Southern Medical University (CN)
Publication Details
- Journal
- Blood Pressure
- Published
- 2025-10-21
- DOI
- https://doi.org/10.1080/08037051.2025.2578177
- Primary Topic
- Cardiac Ischemia and Reperfusion
- Type
- article
- Field-Weighted Citation Impact
- 0.00